Genetic Architecture of Diabetes Risk
Genetic predisposition plays a major role in diabetes susceptibility. Variants influencing allelic penetrance alter glucose regulation. Epigenetic shifts modify chromatin accessibility in metabolic genes. Disrupted transcriptional fidelity affects insulin pathways. Understanding heritability gradients supports early screening and personalized prevention strategies.
Genomic Focus Areas:
- Risk Gene Mapping
- Epigenetic Influence Models
- Predictive Genetic Tools
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